Acne / Birth Control Pill
For some female patients, treatment-resistant acne is caused by excessive production of hormones called androgens. With extra androgens in your system, your oil-producing glands go into high gear — and so does your acne. Several clues can help your doctor identify acne that may be influenced by hormones: acne that appears in adults for the first time; acne flare-ups preceding the menstrual cycle; irregular menstrual cycles; hirsutism (excessive growth of hair or hair in unusual places); and elevated levels of certain androgens in the blood stream.
Adult women and teenage girls whose acne has resisted treatment with antibiotics or topical retinoids may be candidates for hormonal therapy. Once a patient’s acne is identified as hormonally influenced, the doctor will be able to prescribe a number of different therapies, or perhaps a combination of several different drugs; "combination therapy" is often the best approach to this kind of acne. Following are a few common components of therapy for hormonal acne, but remember to consult your doctor before using any of the remedies listed here.
Acne / Birth Control Pill - Oral contraceptives. Birth-control pills (a combination of estrogen and progestin taken orally) are often prescribed for hormonal acne. Low doses of estrogen help suppress the androgens produced by the ovaries, and the newer progestin agents, including desogestrel and norgestimate, are less androgenic than those found in older formulations. While only Ortho Tri-Cyclen and Estro-Step are currently approved by the FDA for this indication, experts agree that low-dose contraceptives improve acne regardless of which formula is used. Consult your gynecologist to find the formula that’s right for you. While side effects are uncommon, some women may experience brownish blotches, or melasma (hyperpigmentation) on the skin. These can be treated with topical bleaching agents.
Acne / Birth Control Pill - Anti-androgens. In combination with oral contraceptives, doctors also may prescribe an anti-androgen ; these drugs inhibit androgen production in the ovaries and adrenal glands and help prevent existing androgens from causing excessive oil production. Spironolactone, a high blood pressure medicine with anti-androgenic properties, has proven quite effective in the treatment of acne. Side effects may include breast tenderness, menstrual irregularities (in women not using oral contraceptives), headache and fatigue; since it's also a diuretic, you may experience frequent urination as well.
NOTE: Spiranolactone is tetrogenic and can cause feminization of a male fetus. If you are sexually active and not taking “the pill,” it’s imperative that you use another form of birth control.
Acne / Birth Control Pill - Corticosteroids. Small doses of corticosteroids, like prednisone or dexamethasone, may curb inflammation and suppress the androgens produced by the adrenal glands. Keep in mind that in some acne sufferers, corticosteroids may actually aggravate acne; they’re most effective when used in combination with oral contraceptives.
In conclusion, if you think your acne is hormonally induced, see your doctor right away. While this kind of acne requires a different course of treatment, it is highly treatable. More about your hormones.
For patients who suffer from moderate to severe acne, doctors may prescribe a combination of topical remedies and oral antibiotics. The most common oral medications used to treat acne are tetracycline, minocycline, doxycycline and erythromycin.
Antibiotics for Acne - HOW THEY WORK
Like Benzoyl Peroxide, antibiotics control breakouts by curbing the body’s production of
P. acnes, the bacteria that causes acne, and decreasing inflammation. This process may take several weeks or months, so be patient. And remember, you’re not “cured” just because your breakouts have subsided. That’s the medicine doing its job — so if you stop taking it, your acne will probably come back. Likewise, doubling up on your medication won’t make your skin clear up twice as fast. Using your topical antibiotics more frequently than prescribed may actually induce greater follicular irritation and plugging, which slows clearing time. And taking your oral medications more often than prescribed won’t help your skin clear faster — but it will increase your chance of experiencing unpleasant side effects.
Antibiotics for Acne - WHERE TO GET THEM
If you have moderate to severe acne, consult your dermatologist; he or she will discuss your options and help you make the best choice. Once you’ve begun treatment, give it time to start working. Keep your doctor apprised of your progress, so he or she can make changes to the course of treatment if necessary. And again, don’t stop using your medication when your skin clears — let your doctor make that call.
Antibiotics for Acne - COMMON SIDE EFFECTS
With most of the antibiotics used to treat acne, side effects may include photosensitivity (higher risk of sunburn), upset stomach, dizziness or lightheadedness, hives, lupus-like symptoms and skin discoloration. Some women report a higher incidence of vaginal yeast infection while taking antibiotics; these can usually be treated with over-the-counter antifungal medication or a prescription antifungal, such as diflucan. Tetracycline is not given to pregnant women or children under 12 years of age because it can discolor developing teeth. Lastly (and least common), because doxycycline is also the treatment of choice for Lyme disease, there is the theoretical possibility that a patient who takes this medication for a long period of time would build a resistance, and therefore be unable to fight Lyme.
LANGKAH - LANGKAH DOWNLOAD
1. Buka Website :
2. Klik Link Di Sebelah Kiri ( Baris Ke Tiga )
3. Setelah Klik Link Di Sebelah Kiri, Silahkan Download Sesuka Anda.
SELAMAT MENIKMATI
Thursday, February 17, 2011
Acne Treatments: The Cheap Option Or The Potent Stuff?
If you scour the shelves of a pharmacy or drug store, you'll most likely find numerous brands of over-the-counter treatment for acne more than you can count with your fingers. among other skin infections,There are likely to be ingredients common to said treatments for skin infections, though none are exactly the same. If the problem is something that your typical medication can handle, it is probably best you consult a skin care professional.
In most cases, these readily available measures achieve the simple goal of alleviating your acne problem without causing any discomfort. Of course, given individual reactions to the chemicals in the skin treatments, that may not always be the case. Prescription medication, which is typically more potent, may also cause the same unwanted side-effects as those that come from over-the-counter products.
Various factors influence the effectiveness of an over-the-counter or prescription acne treatment product. You might be inclined to wonder which of the two would be the best acne medication, with minimal possible side effects. Well, the answer to this is that all medications can potentially cause side effects. Every person's skin will react differently to different drugs or medications.
Let's take a look at this whole thing objectively, shall we? Or at least, with as much objectivity a single person can have. Hopefully, if we do that we can find the best acne medication, or at least something close to it. In theory, there may be no such thing as a “best” medication, as individual skin chemistry can easily get in the way.
First off, over-the-counter medication for your average range of skin infections, let alone acne, is nowhere near as potent as your typical prescription treatment. This may stem from either the differences in the basic chemical composition or how concentrated the key ingredients of the treatments are. A prescription acne treatment may clear up the problem faster, but the potency of the chemicals can cause side effects more readily than the over-the-counter variants. That means that your life can get back to normal a lot faster, seeing as how you've got one less thing to worry about.
However, despite being “less effective” (and that's something that's just this side of being arguable), over-the-counter stuff is significantly cheaper. Unless you've somehow gotten a case of monumentally bad acne, you should go and try an over-the-counter treatment first. They may not be as potent, but they very often can do the job on their own. If they're not helping, you shouldn't hesitate to seek professional help. Medical insurance may or many not entirely cover your costs, as this sort of thing is something that varies depending on the details of your coverage.
The lower potency of the drugs can also be a boon rather than a bane, for some people. You see, every once in a while, the combination of skin, acne, and other factors is going to produce a person with very sensitive skin. The kind of skin that turns red and swells to the size of a grapefruit at the slightest touch of benzoyl peroxide, or something similar. However, lower chemical potency means that you're also less likely to run into a nasty side effect.
There's also the matter of convenience to be considered here. An over-the-counter product is obviously easier to get your hands on. Go to a drug store, find medication for acne that you like or think would work, and pay for it at the counter. Simple, clean, and there's not a whole lot of time involved. In contrast, if you need to get one that's prescription-required, that involves the time to set up the appointment, the consultation, and all that other good stuff.
There's also the matter of an individual's skin. Your skin is unique and how it might react to something is different from how someone else's skin might react. Your skin may be tougher than most, or it can be easier to scar than most. Medications are set to a specific formula when they're made.
Finally, you may want to keep in mind not to mix and match your treatments. Drug interaction is a leading cause of side effects, aside from poor interaction with the patient's skin. Skin infections like acne can be made worse if you mix two treatments together, such as benzoyl peroxide and salicylic acid. The warning about drug interaction holds true even when you mix together over-the-counter medication and prescription ones, even if the two have ingredients in common.
In most cases, these readily available measures achieve the simple goal of alleviating your acne problem without causing any discomfort. Of course, given individual reactions to the chemicals in the skin treatments, that may not always be the case. Prescription medication, which is typically more potent, may also cause the same unwanted side-effects as those that come from over-the-counter products.
Various factors influence the effectiveness of an over-the-counter or prescription acne treatment product. You might be inclined to wonder which of the two would be the best acne medication, with minimal possible side effects. Well, the answer to this is that all medications can potentially cause side effects. Every person's skin will react differently to different drugs or medications.
Let's take a look at this whole thing objectively, shall we? Or at least, with as much objectivity a single person can have. Hopefully, if we do that we can find the best acne medication, or at least something close to it. In theory, there may be no such thing as a “best” medication, as individual skin chemistry can easily get in the way.
First off, over-the-counter medication for your average range of skin infections, let alone acne, is nowhere near as potent as your typical prescription treatment. This may stem from either the differences in the basic chemical composition or how concentrated the key ingredients of the treatments are. A prescription acne treatment may clear up the problem faster, but the potency of the chemicals can cause side effects more readily than the over-the-counter variants. That means that your life can get back to normal a lot faster, seeing as how you've got one less thing to worry about.
However, despite being “less effective” (and that's something that's just this side of being arguable), over-the-counter stuff is significantly cheaper. Unless you've somehow gotten a case of monumentally bad acne, you should go and try an over-the-counter treatment first. They may not be as potent, but they very often can do the job on their own. If they're not helping, you shouldn't hesitate to seek professional help. Medical insurance may or many not entirely cover your costs, as this sort of thing is something that varies depending on the details of your coverage.
The lower potency of the drugs can also be a boon rather than a bane, for some people. You see, every once in a while, the combination of skin, acne, and other factors is going to produce a person with very sensitive skin. The kind of skin that turns red and swells to the size of a grapefruit at the slightest touch of benzoyl peroxide, or something similar. However, lower chemical potency means that you're also less likely to run into a nasty side effect.
There's also the matter of convenience to be considered here. An over-the-counter product is obviously easier to get your hands on. Go to a drug store, find medication for acne that you like or think would work, and pay for it at the counter. Simple, clean, and there's not a whole lot of time involved. In contrast, if you need to get one that's prescription-required, that involves the time to set up the appointment, the consultation, and all that other good stuff.
There's also the matter of an individual's skin. Your skin is unique and how it might react to something is different from how someone else's skin might react. Your skin may be tougher than most, or it can be easier to scar than most. Medications are set to a specific formula when they're made.
Finally, you may want to keep in mind not to mix and match your treatments. Drug interaction is a leading cause of side effects, aside from poor interaction with the patient's skin. Skin infections like acne can be made worse if you mix two treatments together, such as benzoyl peroxide and salicylic acid. The warning about drug interaction holds true even when you mix together over-the-counter medication and prescription ones, even if the two have ingredients in common.
Acne Treatment for Teenagers
Everybody has had to pass through this tumoultous period and the acne that characterizes it. Apart from causing unsightly physical appearance, it carries a multitude of psychological effects that affects teens in different ways, especially if it is of the severe type.
Teens being a very self conscious lot are greatly affected by acne making them have low self esteem. This might lead to them shunning social settings due to perceptions of others.
So what are the social ramifications that this condition brings?
Those suffering from acne have often been accused by their non-acne friends of being overly-sensitive. However the physical and psychological problems suffered by them have been recognized nowadays as being real and efforts have been made to deal with them appropriately.
Acne is every bit as much how you feel as it is about how you look. This is much more so with teens who usually judge by physical appearances. In a society which places high value on the physical, and sets high standards for them to comply to the "norms", teens suffering from acne are particularly disadvantaged.
The teens suffering from acne often feel they are ugly and this feeling might extend with adult acne.
Parents are constantly faced with a dilemma on how to deal with their children who are afflicated with acne and experience feelings of depressions and inferiority.
Often it is difficult to discern whether the psychological traumas passing through the teens are acne related, or are the usual tantrums and emotional phases that characterizes teenage hood.This makes it difficult to understand the psychological effects associated with acne.
The simplest and most effective way of understanding this psychological effects is just listening.By listening to how acne makes them feel and the insecurities it causes them, parents can show that they emphathise with them and care.
Additionaly informing them on the causes , types and treatment can reassure them that they aren't viewed as being dirty or having poor hygiene. Hygiene doesn't directly cause acne.Parents should also let them know that teenagers all over face the same issues with acne, thus showing them that they aren't alone in this.
As stated before, finding out the cause and type of acne is the first step to seeking treatment.Once one begins on a treatment plan, they end up feeling better about their appearance and consequently themselves.
Teens being a very self conscious lot are greatly affected by acne making them have low self esteem. This might lead to them shunning social settings due to perceptions of others.
So what are the social ramifications that this condition brings?
Those suffering from acne have often been accused by their non-acne friends of being overly-sensitive. However the physical and psychological problems suffered by them have been recognized nowadays as being real and efforts have been made to deal with them appropriately.
Acne is every bit as much how you feel as it is about how you look. This is much more so with teens who usually judge by physical appearances. In a society which places high value on the physical, and sets high standards for them to comply to the "norms", teens suffering from acne are particularly disadvantaged.
The teens suffering from acne often feel they are ugly and this feeling might extend with adult acne.
Parents are constantly faced with a dilemma on how to deal with their children who are afflicated with acne and experience feelings of depressions and inferiority.
Often it is difficult to discern whether the psychological traumas passing through the teens are acne related, or are the usual tantrums and emotional phases that characterizes teenage hood.This makes it difficult to understand the psychological effects associated with acne.
The simplest and most effective way of understanding this psychological effects is just listening.By listening to how acne makes them feel and the insecurities it causes them, parents can show that they emphathise with them and care.
Additionaly informing them on the causes , types and treatment can reassure them that they aren't viewed as being dirty or having poor hygiene. Hygiene doesn't directly cause acne.Parents should also let them know that teenagers all over face the same issues with acne, thus showing them that they aren't alone in this.
As stated before, finding out the cause and type of acne is the first step to seeking treatment.Once one begins on a treatment plan, they end up feeling better about their appearance and consequently themselves.
Acne Prevention: Should I See A Dermatologist?
Acne is a skin infection that may be considered as one of the worst things that can happen to a person, especially during the teenage years. Aside from the obvious physical damage it can do, one would also have to contend with things such as the social impact and the psychological damage that it could bring. A person may even have to deal with scarring and inflammation even after the acne is gone.
As with most other medical ailments, it is always a good idea to test first on what medications are available in the market. Depending on how sensitive a person's skin is, one would want to try benzoyl peroxide or salicylic acid as possible treatments for this specific skin infection. One might also consider using both, but at different times in a day. If no improvement is visible after a certain period (typically from six to eight weeks should be enough), then this would be the time that one might want to consider seeking professional help.
A dermatologist would definitely know more about this type of skin infection and how one might handle this problem, not to mention knowing what specific treatments one might need to use if an over-the-counter product just isn't doing the job. One might want to know that prescription treatments are generally more potent and more expensive than the usual medications.
There are a few things to consider when a visit to the dermatologist is needed:
l if over the counter treatments do not have any positive effect on the acne problem;
l if a person has more than one sign of skin infection, such as whiteheads, blackheads, or red spots;
l if the acne appears not just in the face, but also throughout the body;
l if scars are visible on areas where one previously had acne;
l if there is pus filled spots on one's face that is painful when touched or tampered with;
l if there is continuous inflammation in the face; and
l if this skin infection starts to limit one's social interactions.
A person with acne should keep these points in mind whenever he decides to seek help from a dermatologist. Communication with one's dermatologist is important so that a person undergoing treatment can fully discuss the nature of the problem and the ways to continue the treatment at home. Discussions with the dermatologist should be as thorough and accurate as possible. It may be quite embarrassing for some but the consequences of skin infection can be so serious that no one should neglect getting all the information about acne treatment. In addition, one may need to bring a history of their previous acne records so that the doctor or dermatologist can prepare allergy-free treatments and other anti-acne products.
Treatment of acne is not only a medical issue but a matter of great importance to one's self-esteem and personal hygiene. Acne is not only unsightly but also causes embarrassment and a certain degree of social anxiety. But a person with acne need not despair since a lot of treatment options are now available to heal those unsightly inflammations and scars.
As with most other medical ailments, it is always a good idea to test first on what medications are available in the market. Depending on how sensitive a person's skin is, one would want to try benzoyl peroxide or salicylic acid as possible treatments for this specific skin infection. One might also consider using both, but at different times in a day. If no improvement is visible after a certain period (typically from six to eight weeks should be enough), then this would be the time that one might want to consider seeking professional help.
A dermatologist would definitely know more about this type of skin infection and how one might handle this problem, not to mention knowing what specific treatments one might need to use if an over-the-counter product just isn't doing the job. One might want to know that prescription treatments are generally more potent and more expensive than the usual medications.
There are a few things to consider when a visit to the dermatologist is needed:
l if over the counter treatments do not have any positive effect on the acne problem;
l if a person has more than one sign of skin infection, such as whiteheads, blackheads, or red spots;
l if the acne appears not just in the face, but also throughout the body;
l if scars are visible on areas where one previously had acne;
l if there is pus filled spots on one's face that is painful when touched or tampered with;
l if there is continuous inflammation in the face; and
l if this skin infection starts to limit one's social interactions.
A person with acne should keep these points in mind whenever he decides to seek help from a dermatologist. Communication with one's dermatologist is important so that a person undergoing treatment can fully discuss the nature of the problem and the ways to continue the treatment at home. Discussions with the dermatologist should be as thorough and accurate as possible. It may be quite embarrassing for some but the consequences of skin infection can be so serious that no one should neglect getting all the information about acne treatment. In addition, one may need to bring a history of their previous acne records so that the doctor or dermatologist can prepare allergy-free treatments and other anti-acne products.
Treatment of acne is not only a medical issue but a matter of great importance to one's self-esteem and personal hygiene. Acne is not only unsightly but also causes embarrassment and a certain degree of social anxiety. But a person with acne need not despair since a lot of treatment options are now available to heal those unsightly inflammations and scars.
Acne: You Can Fight Acne with Masks
You can fight acne not only with gel or special soaps, but also with natural masks. Masks made of products you easily may find in your kitchen and you easily can make, too. These ones are granted to work. These products have great qualities that are inherent in the most ordinary things that can make you beautiful, cleansing your skin and brightening your complexion.
The mask made of eggs is one of the most common and it is a good method for toning the skin, according to some experts. They say that eggs help tightening your skin, giving you a firmer face, less wrinkled and less prone to sagging.
To make an egg mask is something quite simple and fast that you can not even imagine. First, beat one egg white until it is stiff. After that you just smooth it over your entire face. Then, remove the mask, but after 20 minutes.
You can adjust the mask to your skin type. If your have oily skin, add lemon juice to the egg white (only one drop). And if you have dry skin, put a bit of honey to the egg white. Experts explain that the skin on the inside of the shell can actually work as an acne treatment. Just place the skin over the breakout and leave on for 30 minute or even overnight to help reduce the appearance of the acne.
It is recommended to apply facial masks once a week for best results. Remember rinsing your face first with warm water and then rinsing with cold (to close the pores) after you finish removing the mask.
The mask made of eggs is one of the most common and it is a good method for toning the skin, according to some experts. They say that eggs help tightening your skin, giving you a firmer face, less wrinkled and less prone to sagging.
To make an egg mask is something quite simple and fast that you can not even imagine. First, beat one egg white until it is stiff. After that you just smooth it over your entire face. Then, remove the mask, but after 20 minutes.
You can adjust the mask to your skin type. If your have oily skin, add lemon juice to the egg white (only one drop). And if you have dry skin, put a bit of honey to the egg white. Experts explain that the skin on the inside of the shell can actually work as an acne treatment. Just place the skin over the breakout and leave on for 30 minute or even overnight to help reduce the appearance of the acne.
It is recommended to apply facial masks once a week for best results. Remember rinsing your face first with warm water and then rinsing with cold (to close the pores) after you finish removing the mask.
Acne - How The Acne Scars Are Treated?
Acne scars leave their mark not only on the skin but also on the sufferers psyche. With rapid developments in dermatology, treating acne scars is becoming easier. Please consult your dermatologist about the best treatment for your acne scars. The choice will depend upon your medical history, the type of scar and the kinds of treatments available for that type of scarring. Some treatments are cheaper than others but may not give perfect results. The choice therefore also depends upon your budget and the kind of results you desire. Let us look at the kinds of treatments available for acne scars.
Dermabrasion- this is considered one of the most effective treatments for acne scars. In this procedure the doctor uses a local anesthetic or freezes the skin and then uses a high-speed rotary abrader to remove unwanted surface skin. As the skin heals, it shows a brighter appearance. This procedure may remove superficial scars altogether and reduces deeper scars.
Chemical Peeling - depending on the scar, your doctor will apply a mild chemical peel on the affected skin. This slowly peels away the old skin and brings in fresh skin. Mild scars can be treated with chemical peels.
Laser Therapy- lasers of different types are used by the doctor to give a new shape to the scarred skin by recontouring the scars. The high burst of laser may leave the skin red for sometime.
Soft Tissue Filling- Collagen that may be bovine in source or patients own may be injected below the scar to lift the skin and give a smooth appearance. As the injected collagen gets absorbed in the body over a period, further treatments may be needed after about six months. Similarly fat may be injected below deep scars for giving a lift to the skin. Similar to collagen filling, fat injections may need to be repeated after some months. Your doctor will advise you about that.
Skin surgery- Skin may have to be surgically corrected with grafting or other procedures to remove some scars.
Microdermabrasion- In this procedure very tiny aluminum oxide crystals are passed through a vacuum tube to scrape the surface of the skin. this procedure may have to be repeated many times, an d gives a fresh look to the skin by scraping .Very mild scarring can be treated with microdermabrasion.
For people who have the tendency to form keloids, no surgical method can be used. If one can develop keloid with acne injury, more keloids will be formed by further surgery. steroid injections may be used to treat keloids. In some cases topical retinoic acid is applied directly on the keloids.
This article is only for informative purposes. This article is not intended to be a medical advise and it is not a substitute for professional medical advice. Please consult your doctor for your medical concerns. Please follow any tip given in this article only after consulting your doctor. The author is not liable for any outcome or damage resulting from information obtained from this article.
Dermabrasion- this is considered one of the most effective treatments for acne scars. In this procedure the doctor uses a local anesthetic or freezes the skin and then uses a high-speed rotary abrader to remove unwanted surface skin. As the skin heals, it shows a brighter appearance. This procedure may remove superficial scars altogether and reduces deeper scars.
Chemical Peeling - depending on the scar, your doctor will apply a mild chemical peel on the affected skin. This slowly peels away the old skin and brings in fresh skin. Mild scars can be treated with chemical peels.
Laser Therapy- lasers of different types are used by the doctor to give a new shape to the scarred skin by recontouring the scars. The high burst of laser may leave the skin red for sometime.
Soft Tissue Filling- Collagen that may be bovine in source or patients own may be injected below the scar to lift the skin and give a smooth appearance. As the injected collagen gets absorbed in the body over a period, further treatments may be needed after about six months. Similarly fat may be injected below deep scars for giving a lift to the skin. Similar to collagen filling, fat injections may need to be repeated after some months. Your doctor will advise you about that.
Skin surgery- Skin may have to be surgically corrected with grafting or other procedures to remove some scars.
Microdermabrasion- In this procedure very tiny aluminum oxide crystals are passed through a vacuum tube to scrape the surface of the skin. this procedure may have to be repeated many times, an d gives a fresh look to the skin by scraping .Very mild scarring can be treated with microdermabrasion.
For people who have the tendency to form keloids, no surgical method can be used. If one can develop keloid with acne injury, more keloids will be formed by further surgery. steroid injections may be used to treat keloids. In some cases topical retinoic acid is applied directly on the keloids.
This article is only for informative purposes. This article is not intended to be a medical advise and it is not a substitute for professional medical advice. Please consult your doctor for your medical concerns. Please follow any tip given in this article only after consulting your doctor. The author is not liable for any outcome or damage resulting from information obtained from this article.
Acne: Asthma Drug Fails to Help Patients with Acne
The asthma drug Zyflo fails to help patients with severe acne, according to a mid-stage trial carried out by the company Critical Therapeutics Inc. The drug, also known as zileuton, was neither better at controlling the number of inflammatory lesions than placebos under the company statistics.
Over the 12-week trial, patients treated with Zyflo had an average reduction of 11.5 inflammatory lesions. That compared with a reduction of 9.1 lesions in a group of other patients taking placebos – far short of achieving statistical significance.
Patients treated with placebo showed a reduction of 16.4 lesions in the placebo group, but patients treated with Zyflo showed a mean reduction in the total number of lesions of 25.3.
The company stated the medicine showed a trend of potential benefit to some patients although the drug failed the primary goal of the trial.
Linda Lennox, the company spokeswoman, told the company will probably conduct a larger trial testing the medicine as an acne treatment, using information gleaned from the small recent "proof of concept" trial.
The company based in Lexington, Massachusetts, said that it is continuing to analyze the data and is working with the investigators to further interpret the results.
Zyflo blocks an inflammation-causing enzyme called 5 lipoxygenase (5-LO). It was approved by U.S. regulators in 1996 for treating asthma patients 12 years of age and older. At the time, the drug was owned by Abbott Laboratories Inc., which sold it for a number of years before licensing it to Critical Therapeutics in late 2003.
Over the 12-week trial, patients treated with Zyflo had an average reduction of 11.5 inflammatory lesions. That compared with a reduction of 9.1 lesions in a group of other patients taking placebos – far short of achieving statistical significance.
Patients treated with placebo showed a reduction of 16.4 lesions in the placebo group, but patients treated with Zyflo showed a mean reduction in the total number of lesions of 25.3.
The company stated the medicine showed a trend of potential benefit to some patients although the drug failed the primary goal of the trial.
Linda Lennox, the company spokeswoman, told the company will probably conduct a larger trial testing the medicine as an acne treatment, using information gleaned from the small recent "proof of concept" trial.
The company based in Lexington, Massachusetts, said that it is continuing to analyze the data and is working with the investigators to further interpret the results.
Zyflo blocks an inflammation-causing enzyme called 5 lipoxygenase (5-LO). It was approved by U.S. regulators in 1996 for treating asthma patients 12 years of age and older. At the time, the drug was owned by Abbott Laboratories Inc., which sold it for a number of years before licensing it to Critical Therapeutics in late 2003.
Subscribe to:
Posts (Atom)